Why is FTIR important?

What is the importance of FTIR?

FTIR is widely used in many industries and is used for the analysis of both organic and inorganic compounds. It can confirm the composition of both solids, liquids, and gases. FTIR is mainly used for: The identification of unknown compounds.

How FTIR is practically useful in your research?

FTIR is an extremely useful technique for confirming the identity of pure compounds, but has limited value if used for mixtures of compounds. … These vibrations and their intensity (% transmission) are plotted against the frequency of light (cm−1) to which the sample is exposed to produce an FTIR spectrum.

What kind of information do you get from FTIR?

FTIR is a rapid, nondestructive, time saving method that can detect a range of functional groups and is sensitive to changes in molecular structure. FTIR provide information on the basis of chemical composition and physical state of the whole sample (Cocchi et al. 2004).

What application do you think the FTIR has in pharmaceutical sciences?

FTIR is an excellent technique for pharmaceutical analysis because it is easy to use, sensitive, fast, and helps ensure regulatory compliance through validation protocols. Applications include: Basic drug research and structural elucidation. Formulation development and validation.

What is the working principle of FTIR?

FTIR spectrometers rely on the same basic principle as NDIR analyzers, i.e., the fact that many gases absorb IR radiation at species-specific frequencies. However, FTIR spectroscopy is a disperse method, which means that measurements are performed over a broad spectrum instead of a narrow band of frequencies.

How do you use FTIR for quantitative analysis?

Prepare known concentrations of your samples and analyze. For this you must know the prominent IR peak in your sample. Measure peak heights/areas and prepare a calibration curve. From this you can determine the concentration in unknown sample by noting peak height.

What is FTIR and why is it called absorption technique?

Fourier-transform infrared spectroscopy (FTIR) is a technique used to obtain an infrared spectrum of absorption or emission of a solid, liquid or gas. An FTIR spectrometer simultaneously collects high-resolution spectral data over a wide spectral range.

Can FTIR detect metals?

The 4100 ExoScan FTIR and the 4300 Handheld FTIR with a grazing angle sample interface enables identification and quantification of metal surface cleanliness in the field. After the metal has been cleaned, the analyzer can be used to detect the presence of organic and some inorganic contaminants.